ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp

Platelet factor 4 (PF4) is an anti-Plasmodium component of platelets. It is expressed in megakaryocytes and released from platelets following infection with Plasmodium. Innate immunity is crucial for the host anti-Plasmodium response, in which type I interferon plays an important role. Whether there...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Wang, Dandan, Zhang, Zeming, Cui, Shuang, Zhao, Yingchi, Craft, Samuel, Fikrig, Erol, You, Fuping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514618/
https://ncbi.nlm.nih.gov/pubmed/30898878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006321
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