Suppression of ELF4 in ulcerative colitis predisposes host to colorectal cancer

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, characterized by relapsing and remitting colon mucosal inflammation. For patients suffering from UC, a higher risk of colon cancer has been widely recognized. Here, we found that Elf4(−/−) mice developed colon tumors with 3 cycles of d...

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Bibliografski detalji
Izdano u:iScience
Glavni autori: Du, Hongqiang, Xia, Huawei, Liu, Tongtong, Li, Yingjie, Liu, Jilong, Xie, Bingteng, Chen, Jingxuan, Liu, Tong, Cao, Lili, Liu, Shengde, Li, Siji, Wang, Peiyan, Wang, Dandan, Zhang, Zeming, Li, Yunfei, Guo, Xiaohuan, Wu, Aiwen, Li, Mo, You, Fuping
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907480/
https://ncbi.nlm.nih.gov/pubmed/33665583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102169
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