Nlrp6 regulates intestinal antiviral innate immunity

The nucleotide-binding oligomerization domain-like receptor (Nlrp) 6 maintains gut microbiota homeostasis and regulates antibacterial immunity. We now report a role for Nlrp6 in the control of enteric virus infection. Nlrp6(−/−) and control mice systemically challenged with encephalomyocarditis viru...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Wang, Penghua, Zhu, Shu, Yang, Long, Cui, Shuang, Pan, Wen, Jackson, Ruaidhri, Zheng, Yunjiang, Rongvaux, Anthony, Sun, Qiangming, Yang, Guang, Gao, Shandian, Lin, Rongtuan, You, Fuping, Flavell, Richard, Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927078/
https://ncbi.nlm.nih.gov/pubmed/26494172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab3145
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