UBXN1 Interferes with Rig-I-like Receptor-Mediated Antiviral Immune Response by Targeting MAVS

RNA viruses are sensed by RIG-I-like receptors (RLRs), which signal through a mitochondria-associated adaptor molecule, MAVS, resulting in systemic antiviral immune responses. Although RLR signaling is essential for limiting RNA virus replication, it must be stringently controlled to prevent damage...

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Autores principales: Wang, Penghua, Yang, Long, Cheng, Gong, Yang, Guang, Xu, Zhengyun, You, Fuping, Sun, Qiang, Lin, Rongtuan, Fikrig, Erol, Sutton, Richard E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707122/
https://ncbi.nlm.nih.gov/pubmed/23545497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.027
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