Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα

UBXN proteins likely participate in the global regulation of protein turnover, and we have shown that UBXN1 interferes with RIG-I-like receptor (RLR) signaling by interacting with MAVS and impeding its downstream effector functions. Here we demonstrate that over-expression of multiple UBXN family me...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hu, Yani, O’Boyle, Kaitlin, Auer, Jim, Raju, Sagar, You, Fuping, Wang, Penghua, Fikrig, Erol, Sutton, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308826/
https://ncbi.nlm.nih.gov/pubmed/28152074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006187
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