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HIPK2 is necessary for type I interferon–mediated antiviral immunity
Precise control of interferons (IFNs) is crucial to maintain immune homeostasis. Here, we demonstrated that homeodomain-interacting protein kinase 2 (HIPK2) was required for the production of type I IFNs in response to RNA virus infection. HIPK2 deficiency markedly impaired IFN production in macroph...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893850/ https://ncbi.nlm.nih.gov/pubmed/30890658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau4604 |
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