Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk

The nuclear bile acid receptor farnesoid X receptor (FXR) is an important transcriptional regulator of bile acid, lipid, and glucose metabolism. FXR is highly expressed in the liver and intestine and controls the synthesis and enterohepatic circulation of bile acids. However, little is known about F...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lien, Fleur, Berthier, Alexandre, Bouchaert, Emmanuel, Gheeraert, Céline, Alexandre, Jeremy, Porez, Geoffrey, Prawitt, Janne, Dehondt, Hélène, Ploton, Maheul, Colin, Sophie, Lucas, Anthony, Patrice, Alexandre, Pattou, François, Diemer, Hélène, Van Dorsselaer, Alain, Rachez, Christophe, Kamilic, Jelena, Groen, Albert K., Staels, Bart, Lefebvre, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938262/
https://ncbi.nlm.nih.gov/pubmed/24531544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68815
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge