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An optimized protocol with a stepwise approach to identify specific nuclear receptor ligands from cultured mammalian cells

Here, we describe an optimized protocol to identify specific nuclear receptor ligands. First, to rule out any compound interference with luciferase activity per se, we describe an in vitro assay assessing potential inhibition or activation of luciferase enzymatic activity. Second, to comply with EMA...

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Foilsithe in:STAR Protoc
Main Authors: Berthier, Alexandre, Staels, Bart, Lefebvre, Philippe
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273406/
https://ncbi.nlm.nih.gov/pubmed/34286290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100658
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