Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk

The nuclear bile acid receptor farnesoid X receptor (FXR) is an important transcriptional regulator of bile acid, lipid, and glucose metabolism. FXR is highly expressed in the liver and intestine and controls the synthesis and enterohepatic circulation of bile acids. However, little is known about F...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lien, Fleur, Berthier, Alexandre, Bouchaert, Emmanuel, Gheeraert, Céline, Alexandre, Jeremy, Porez, Geoffrey, Prawitt, Janne, Dehondt, Hélène, Ploton, Maheul, Colin, Sophie, Lucas, Anthony, Patrice, Alexandre, Pattou, François, Diemer, Hélène, Van Dorsselaer, Alain, Rachez, Christophe, Kamilic, Jelena, Groen, Albert K., Staels, Bart, Lefebvre, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938262/
https://ncbi.nlm.nih.gov/pubmed/24531544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68815
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados