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megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering

Rare-cleaving endonucleases have emerged as important tools for making targeted genome modifications. While multiple platforms are now available to generate reagents for research applications, each existing platform has significant limitations in one or more of three key properties necessary for the...

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書誌詳細
主要な著者: Boissel, Sandrine, Jarjour, Jordan, Astrakhan, Alexander, Adey, Andrew, Gouble, Agnès, Duchateau, Philippe, Shendure, Jay, Stoddard, Barry L., Certo, Michael T., Baker, David, Scharenberg, Andrew M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936731/
https://ncbi.nlm.nih.gov/pubmed/24285304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1224
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