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Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data

Many studies have identified binding preferences for transcription factors (TFs), but few have yielded predictive models of how combinations of transcription factor binding sites generate specific levels of gene expression. Synthetic promoters have emerged as powerful tools for generating quantitati...

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Autori principali: Zeigler, Robert D., Cohen, Barak A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936720/
https://ncbi.nlm.nih.gov/pubmed/24288374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1230
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