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Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data

Many studies have identified binding preferences for transcription factors (TFs), but few have yielded predictive models of how combinations of transcription factor binding sites generate specific levels of gene expression. Synthetic promoters have emerged as powerful tools for generating quantitati...

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Bibliografiske detaljer
Main Authors: Zeigler, Robert D., Cohen, Barak A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936720/
https://ncbi.nlm.nih.gov/pubmed/24288374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1230
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