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Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
The master tumor suppressor p53 controls transcription of a wide-ranging gene network involved in apoptosis, cell cycle arrest, DNA damage repair, and senescence. Recent studies revealed pervasive binding of p53 to cis-regulatory elements (CREs), which are non-coding segments of DNA that spatially a...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7192610/ https://ncbi.nlm.nih.gov/pubmed/32133495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa147 |
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