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Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization
The oncogenic transcription factor B-Myb is an essential regulator of late cell cycle genes whose activation by phosphorylation is still poorly understood. We describe a stepwise phosphorylation mechanism of B-Myb, which involves sequential phosphorylations mediated by cyclin-dependent kinase (Cdk)...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326806/ https://ncbi.nlm.nih.gov/pubmed/30321399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky935 |
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