Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells

Lysine acetylation regulates transcription by targeting histones and nonhistone proteins. Here we report that the central regulator of transcription, RNA polymerase II, is subject to acetylation in mammalian cells. Acetylation occurs at eight lysines within the C-terminal domain (CTD) of the largest...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schröder, Sebastian, Herker, Eva, Itzen, Friederike, He, Daniel, Thomas, Sean, Gilchrist, Daniel A., Kaehlcke, Katrin, Cho, Sungyoo, Pollard, Katherine S., Capra, John A., Schnölzer, Martina, Cole, Philip A., Geyer, Matthias, Bruneau, Benoit G., Adelman, Karen, Ott, Melanie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936344/
https://ncbi.nlm.nih.gov/pubmed/24207025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.009
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