Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells

Lysine acetylation regulates transcription by targeting histones and nonhistone proteins. Here we report that the central regulator of transcription, RNA polymerase II, is subject to acetylation in mammalian cells. Acetylation occurs at eight lysines within the C-terminal domain (CTD) of the largest...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schröder, Sebastian, Herker, Eva, Itzen, Friederike, He, Daniel, Thomas, Sean, Gilchrist, Daniel A., Kaehlcke, Katrin, Cho, Sungyoo, Pollard, Katherine S., Capra, John A., Schnölzer, Martina, Cole, Philip A., Geyer, Matthias, Bruneau, Benoit G., Adelman, Karen, Ott, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936344/
https://ncbi.nlm.nih.gov/pubmed/24207025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados