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Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
The bromodomain protein Brd4 regulates the transcription of signal-inducible genes. This is achieved by recruiting the positive transcription elongation factor P-TEFb to promoters by its P-TEFb interaction domain (PID). Here we show that Brd4 stimulates the kinase activity of P-TEFb for phosphorylat...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081074/ https://ncbi.nlm.nih.gov/pubmed/24860166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku449 |
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