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Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution

Brd4 is a member of the bromodomains and extra terminal domain (BET) family of proteins that recognize acetylated chromatin structures through their bromodomains and act as transcriptional activators. Brd4 functions as an associated factor and positive regulator of P-TEFb, a Cdk9-cyclin T heterodime...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Vollmuth, Friederike, Blankenfeldt, Wulf, Geyer, Matthias
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794770/
https://ncbi.nlm.nih.gov/pubmed/19828451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033712
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