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Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells
The elongation competence of the RNA polymerase II complex is critically dependent on the positive transcription elongation factor b (P-TEFb). P-TEFb exists in two forms in cells, an active form composed of cyclin T1 and CDK9 and an inactive form, in which cyclin T1/CDK9 is sequestered by Hexim1 and...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688543/ https://ncbi.nlm.nih.gov/pubmed/19387490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.99 |
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