Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)

The essential transactivator function of the HIV Tat protein is regulated by multiple posttranslational modifications. Although individual modifications are well characterized, their crosstalk and dynamics of occurrence during the HIV transcription cycle remain unclear. We examine interactions betwe...

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Bibliografiske detaljer
Main Authors: Sakane, Naoki, Kwon, Hye-Sook, Pagans, Sara, Kaehlcke, Katrin, Mizusawa, Yasuhiro, Kamada, Masafumi, Lassen, Kara G., Chan, Jonathan, Greene, Warner C., Schnoelzer, Martina, Ott, Melanie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158049/
https://ncbi.nlm.nih.gov/pubmed/21876670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002184
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