Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Por Ando, Izuru, Adachi, Tsuyoshi, Ogura, Naoki, Toyonaga, Yukiyo, Sugimoto, Kazuyuki, Abe, Hiroyuki, Kamada, Masafumi, Noguchi, Toru
Publicado em 2012

Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)

Por Sakane, Naoki, Kwon, Hye-Sook, Pagans, Sara, Kaehlcke, Katrin, Mizusawa, Yasuhiro, Kamada, Masafumi, Lassen, Kara G., Chan, Jonathan, Greene, Warner C., Schnoelzer, Martina, Ott, Melanie
Publicado em 2011

The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7

Por Ali, Ibraheem, Ramage, Holly, Boehm, Daniela, Dirk, Lynnette M. A., Sakane, Naoki, Hanada, Kazuki, Pagans, Sara, Kaehlcke, Katrin, Aull, Katherine, Weinberger, Leor, Trievel, Raymond, Schnoelzer, Martina, Kamada, Masafumi, Houtz, Robert, Ott, Melanie
Publicado no J Biol Chem (2016)

SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious RORγ Inhibitor

Por Hirata, Kazuyuki, Kotoku, Masayuki, Seki, Noriyoshi, Maeba, Takaki, Maeda, Katsuya, Hirashima, Shintaro, Sakai, Takayuki, Obika, Shingo, Hori, Akimi, Hase, Yasunori, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Hata, Takahiro, Miyagawa, Naoki, Arita, Kojo, Nomura, Yukihiro, Asahina, Kota, Aratsu, Yusuke, Kamada, Masafumi, Adachi, Tsuyoshi, Noguchi, Masato, Doi, Satoki, Crowe, Paul, Bradley, Erin, Steensma, Ruo, Tao, Haiyan, Fenn, Morgan, Babine, Robert, Li, Xiaolin, Thacher, Scott, Hashimoto, Hiromasa, Shiozaki, Makoto
Publicado no ACS Med Chem Lett (2015)