Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma

Given the frequent and largely incurable occurrence of multiple myeloma (MM), identification of germline genetic mutations that predispose cells to MM may provide insight into disease etiology and the developmental mechanisms of its cell of origin, the plasma cell. Here we identified familial and ea...

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Publicado no:Cancer Res
Main Authors: Wei, Xiaomu, Calvo-Vidal, M. Nieves, Chen, Siwei, Wu, Gang, Revuelta, Maria V., Sun, Jian, Zhang, Jinghui, Walsh, Michael F., Nichols, Kim E., Joseph, Vijai, Snyder, Carrie, Vachon, Celine M., McKay, James D., Wang, Shu-Ping, Jayabalan, David S., Jacobs, Lauren M., Becirovic, Dina, Waller, Rosalie G., Artomov, Mykyta, Viale, Agnes, Patel, Jayeshkumar, Phillip, Jude, Chen-Kiang, Selina, Curtin, Karen, Salama, Mohamed, Atanackovic, Djordje, Niesvizky, Ruben, Landgren, Ola, Slager, Susan L., Godley, Lucy A., Churpek, Jane, Garber, Judy E., Anderson, Kenneth C., Daly, Mark J., Roeder, Robert G., Dumontet, Charles, Lynch, Henry T., Mullighan, Charles G., Camp, Nicola J., Offit, Ken, Klein, Robert J., Yu, Haiyuan, Cerchietti, Leandro, Lipkin, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955848/
https://ncbi.nlm.nih.gov/pubmed/29559475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1900
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