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Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

T cell receptor (TCR) activation leads to a dramatic reorganisation of both membranes and receptors as the immunological synapse forms. Using a genetic model to rapidly inhibit Zap70 catalytic activity we examined synapse formation between cytotoxic T lymphocytes and their targets. In the absence of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jenkins, Misty R, Stinchcombe, Jane C, Au-Yeung, Byron B, Asano, Yukako, Ritter, Alex T, Weiss, Arthur, Griffiths, Gillian M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936284/
https://ncbi.nlm.nih.gov/pubmed/24596147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01310
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