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Regulation of UDP-Glucuronosyltransferase 1A1 Expression and Activity by MicroRNA 491-3p

The UDP-glucuronosyltransferase (UGT) 1A enzymes are involved in the phase II metabolism of many important endogenous and exogenous compounds. The nine UGT1A isoforms exhibit high interindividual differences in expression, but their epigenetic regulation is not well understood. The purpose of the pr...

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Autori principali: Dluzen, Douglas F., Sun, Dongxiao, Salzberg, Anna C., Jones, Nate, Bushey, Ryan T., Robertson, Gavin P., Lazarus, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935146/
https://ncbi.nlm.nih.gov/pubmed/24399855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.210658
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