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Regulation of UDP-Glucuronosyltransferase 1A1 Expression and Activity by MicroRNA 491-3p

The UDP-glucuronosyltransferase (UGT) 1A enzymes are involved in the phase II metabolism of many important endogenous and exogenous compounds. The nine UGT1A isoforms exhibit high interindividual differences in expression, but their epigenetic regulation is not well understood. The purpose of the pr...

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Detalhes bibliográficos
Main Authors: Dluzen, Douglas F., Sun, Dongxiao, Salzberg, Anna C., Jones, Nate, Bushey, Ryan T., Robertson, Gavin P., Lazarus, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935146/
https://ncbi.nlm.nih.gov/pubmed/24399855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.210658
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