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Regulation of UDP-Glucuronosyltransferase 1A1 Expression and Activity by MicroRNA 491-3p

The UDP-glucuronosyltransferase (UGT) 1A enzymes are involved in the phase II metabolism of many important endogenous and exogenous compounds. The nine UGT1A isoforms exhibit high interindividual differences in expression, but their epigenetic regulation is not well understood. The purpose of the pr...

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Hlavní autoři: Dluzen, Douglas F., Sun, Dongxiao, Salzberg, Anna C., Jones, Nate, Bushey, Ryan T., Robertson, Gavin P., Lazarus, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935146/
https://ncbi.nlm.nih.gov/pubmed/24399855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.210658
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