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Regulation of UGT1A1 expression and activity by miR-491-3p*

The UDP-glucuronosyltransferase (UGT) 1A enzymes are involved in the phase II metabolism of many important endogenous and exogenous compounds. The nine UGT1A isoforms exhibit high inter-individual differences in expression but their epigenetic regulation is not well-understood. The purpose of the pr...

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Podrobná bibliografie
Vydáno v:Drug Metab Rev
Hlavní autoři: Dluzen, Douglas F., Sun, Dongxiao, Salzberg, Anna C., Jones, Nate, Bushey, Ryan T., Robertson, Gavin P., Lazarus, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309899/
https://ncbi.nlm.nih.gov/pubmed/26300547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602532.2015.1076438
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