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PIAS1 Regulates Breast Tumorigenesis through Selective Epigenetic Gene Silencing
Epigenetic gene silencing by histone modifications and DNA methylation is essential for cancer development. The molecular mechanism that promotes selective epigenetic changes during tumorigenesis is not understood. We report here that the PIAS1 SUMO ligase is involved in the progression of breast tu...
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| Main Authors: | , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933565/ https://ncbi.nlm.nih.gov/pubmed/24586797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089464 |
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