Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis

nc886 (= vtRNA2-1 or pre-miR-886) is a recently discovered noncoding RNA that is a cellular PKR (Protein Kinase RNA-activated) ligand and repressor. nc886 has been suggested to be a tumor suppressor, solely based on its expression pattern and genomic locus. In this report, we have provided sufficien...

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Bibliografiske detaljer
Main Authors: Lee, Hyun-Sung, Lee, Kwanbok, Jang, Hee-Jin, Lee, Geon Kook, Park, Jong-Lyul, Kim, Seon-Young, Kim, Sang-Bae, Johnson, Betty H., Zo, Jae Ill, Lee, Ju-Seog, Lee, Yong Sun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116496/
https://ncbi.nlm.nih.gov/pubmed/25004084
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