From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II

RNA polymerase II (RNAPII) lies at the core of dynamic control of gene expression. Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cerevisiae. This analysis enabled functional assign...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Braberg, Hannes, Jin, Huiyan, Moehle, Erica A., Chan, Yujia A., Wang, Shuyi, Shales, Michael, Benschop, Joris J., Morris, John H., Qiu, Chenxi, Hu, Fuqu, Tang, Leung K., Fraser, James S., Holstege, Frank C.P., Hieter, Philip, Guthrie, Christine, Kaplan, Craig D., Krogan, Nevan J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932829/
https://ncbi.nlm.nih.gov/pubmed/23932120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.033
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires