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Engineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules
To facilitate the therapeutic application of antigen-presenting cells (APCs), we have developed a cell-based artificial APC (aAPC) system by engineering K562 cells with lentiviruses to direct the stable expression and secretion of a variety of co-stimulatory molecules and cytokines. Here we report t...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932757/ https://ncbi.nlm.nih.gov/pubmed/17375070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.sj.6300134 |
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