The Inducible Costimulator (ICOS) Is Critical for the Development of Human T(H)17 Cells

Human T helper 17 (T(H)17) cells regulate host defense, autoimmunity, and tumor immunity. Although cytokines that control human T(H)17 cell development have been identified, the costimulatory molecules important for T(H)17 cell generation are unknown. Here, we found that the inducible costimulator (...

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Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Paulos, Chrystal M., Carpenito, Carmine, Plesa, Gabriela, Suhoski, Megan M., Varela-Rohena, Angel, Golovina, Tatiana N., Carroll, Richard G., Riley, James L., June, Carl H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282816/
https://ncbi.nlm.nih.gov/pubmed/20980695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000448
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