Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

Mesothelin is a cell-surface molecule over-expressed on a large fraction of carcinomas, and thus is an attractive target of immunotherapy. A molecularly targeted therapy for these cancers was created by engineering T cells to express a chimeric receptor with high affinity for human mesothelin. Lenti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carpenito, Carmine, Milone, Michael C., Hassan, Raffit, Simonet, Jacqueline C., Lakhal, Mehdi, Suhoski, Megan M., Varela-Rohena, Angel, Haines, Kathleen M., Heitjan, Daniel F., Albelda, Steven M., Carroll, Richard G., Riley, James L., Pastan, Ira, June, Carl H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651342/
https://ncbi.nlm.nih.gov/pubmed/19211796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813101106
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak