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Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes

BACKGROUND: Development of a standardized platform for the rapid expansion of tumor-infiltrating lymphocytes (TILs) with anti-tumor function from patients with limited TIL numbers or tumor tissues challenges their clinical application. METHODS: To facilitate adoptive immunotherapy, we applied geneti...

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Detalhes bibliográficos
Main Authors: Ye, Qunrui, Loisiou, Maria, Levine, Bruce L, Suhoski, Megan M, Riley, James L, June, Carl H, Coukos, George, Powell, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162913/
https://ncbi.nlm.nih.gov/pubmed/21827675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-131
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