Llwytho...

Optimization of Antitumor Modulators of Pre-mRNA Splicing

The spliceosome regulates pre-mRNA splicing, which is a critical process in normal mammalian cells. Recently recurrent mutations in numerous spliceosomal proteins have been associated with a number of cancers. Previously natural product antitumor agents have been shown to interact with one of the pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lagisetti, Chandraiah, Palacios, Gustavo, Goronga, Tinopiwa, Freeman, Burgess, Caufield, William, Webb, Thomas R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932738/
https://ncbi.nlm.nih.gov/pubmed/24325474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401370h
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