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Transforming Growth Factor-β(1) Represses Bone Morphogenetic Protein–Mediated Smad Signaling in Pulmonary Artery Smooth Muscle Cells via Smad3

Previous studies of pulmonary arterial hypertension (PAH) have implicated excessive transforming growth factor (TGF)-β(1) signaling and reduced bone morphogenetic protein (BMP) signaling in the disease pathogenesis. Reduced BMP signaling in pulmonary artery smooth muscle cells (PASMCs) from patients...

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Bibliografski detalji
Glavni autori: Upton, Paul D., Davies, Rachel J., Tajsic, Tamara, Morrell, Nicholas W.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931109/
https://ncbi.nlm.nih.gov/pubmed/23937428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0470OC
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