Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA.
Double-stranded RNA inhibits protein synthesis in at least two ways. It activates a protein kinase that blocks peptide chain initiation by phosphorylating the peptide chain initiation factor eIF-2 and also activates an endonuclease that inactivates different mRNAs at different rates. The protein kin...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1978
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5893 |
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