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Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA.

Double-stranded RNA inhibits protein synthesis in at least two ways. It activates a protein kinase that blocks peptide chain initiation by phosphorylating the peptide chain initiation factor eIF-2 and also activates an endonuclease that inactivates different mRNAs at different rates. The protein kin...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Farrell, P J, Sen, G C, Dubois, M F, Ratner, L, Slattery, E, Lengyel, P
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5893
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