2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA.

2-Aminopurine (2-AP) inhibits specific kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2. One of these, PKR, is also involved in signal transduction. We show here that 2-AP selectively inhibits expression of tumor necrosis factor alpha (TNF-alpha) mRNA in pri...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Jarrous, N, Osman, F, Kaempfer, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2814
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