2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA.
2-Aminopurine (2-AP) inhibits specific kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2. One of these, PKR, is also involved in signal transduction. We show here that 2-AP selectively inhibits expression of tumor necrosis factor alpha (TNF-alpha) mRNA in pri...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1996
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2814 |
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