Molecular, genetic and stem cell-mediated therapeutic strategies for spinal muscular atrophy (SMA)

Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease. It is the first genetic cause of infant mortality. It is caused by mutations in the survival motor neuron 1 (SMN1) gene, leading to the reduction of SMN protein. The most striking component is the loss of alpha motor neuro...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Zanetta, Chiara, Riboldi, Giulietta, Nizzardo, Monica, Simone, Chiara, Faravelli, Irene, Bresolin, Nereo, Comi, Giacomo P, Corti, Stefania
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons Ltd 2014
Teme:
Reviews
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930406/
https://ncbi.nlm.nih.gov/pubmed/24400925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12224
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki