Molecular, genetic and stem cell-mediated therapeutic strategies for spinal muscular atrophy (SMA)

Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease. It is the first genetic cause of infant mortality. It is caused by mutations in the survival motor neuron 1 (SMN1) gene, leading to the reduction of SMN protein. The most striking component is the loss of alpha motor neuro...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Zanetta, Chiara, Riboldi, Giulietta, Nizzardo, Monica, Simone, Chiara, Faravelli, Irene, Bresolin, Nereo, Comi, Giacomo P, Corti, Stefania
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Ltd 2014
Témata:
Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930406/
https://ncbi.nlm.nih.gov/pubmed/24400925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12224
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky