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Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints

We have previously reported that ES-62, a molecule secreted by the parasitic filarial nematode Acanthocheilonema viteae, protects mice from developing collagen-induced arthritis (CIA). Together with increasing evidence that worm infection may protect against autoimmune conditions, this raises the po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rodgers, David T, Pineda, Miguel A, McGrath, Mairi A, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930382/
https://ncbi.nlm.nih.gov/pubmed/24708419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12208
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