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Patient-derived tumour xenografts as models for oncology drug development
Progress in oncology drug development has been hampered by a lack of preclinical models that reliably predict clinical activity of novel compounds in cancer patients. In an effort to address these shortcomings, there has been a recent increase in the use of patient-derived tumour xenografts (PDTX) e...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2012
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928688/ https://ncbi.nlm.nih.gov/pubmed/22508028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2012.61 |
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