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A Human Artificial Chromosome Recapitulates the Metabolism of Native Telomeres in Mammalian Cells
Telomeric and subtelomeric regions of human chromosomes largely consist of highly repetitive and redundant DNA sequences, resulting in a paucity of unique DNA sequences specific to individual telomeres. Accordingly, it is difficult to analyze telomere metabolism on a single-telomere basis. To circum...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928237/ https://ncbi.nlm.nih.gov/pubmed/24558398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088530 |
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