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Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential

Glioblastoma multiforme (GBM) is the most common and devastating primary brain tumor among adults. Despite recent treatment progress, most patients succumb to their disease within 2 years of diagnosis. Current research has highlighted the importance of a subpopulation of cells, assigned brain cancer...

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Main Authors: Stockhausen, Marie-Thérése, Kristoffersen, Karina, Stobbe, Louise, Poulsen, Hans Skovgaard
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928138/
https://ncbi.nlm.nih.gov/pubmed/24525857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.26736
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