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Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures

Background: Brain cancer stem-like cells (bCSC) are cancer cells with neural stem cell (NSC)-like properties found in glioblastoma multiforme (GBM) and they are assigned a central role in tumor initiation, progression and relapse. The Notch pathway is important for maintenance and cell fate decision...

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主要な著者: Kristoffersen, Karina, Villingshøj, Mette, Poulsen, Hans Skovgaard, Stockhausen, Marie-Thérése
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742492/
https://ncbi.nlm.nih.gov/pubmed/23792644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.24595
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