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Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures
Background: Brain cancer stem-like cells (bCSC) are cancer cells with neural stem cell (NSC)-like properties found in glioblastoma multiforme (GBM) and they are assigned a central role in tumor initiation, progression and relapse. The Notch pathway is important for maintenance and cell fate decision...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742492/ https://ncbi.nlm.nih.gov/pubmed/23792644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.24595 |
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