P01.20 EPIGENETIC TREATMENT AND INDUCTION OF DIFFERENTIATION IN GLIOBLASTOMA MULTIFORME NEUROSPHERE CELLS LEADS TO DOWNREGULATION OF EGFR, EGFRVIII AND NESTIN TOGETHER WITH REDUCED COLONY FORMATION IN VITRO

It is suggested that Glioblastoma Multiforme (GBM) tumors contain a subpopulation of cells with stem cell features, termed brain cancer stem-like cells (bCSC), which are thought to be involved in tumorigenesis, treatment resistance and recurrence. The epidermal growth factor receptor (EGFR) and the...

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Bibliografiska uppgifter
Huvudupphovsmän: Staberg, M., Villingshøj, M., Stockhausen, M., Poulsen, H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Poster Presentations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185454/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.113
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