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P01.20 EPIGENETIC TREATMENT AND INDUCTION OF DIFFERENTIATION IN GLIOBLASTOMA MULTIFORME NEUROSPHERE CELLS LEADS TO DOWNREGULATION OF EGFR, EGFRVIII AND NESTIN TOGETHER WITH REDUCED COLONY FORMATION IN VITRO
It is suggested that Glioblastoma Multiforme (GBM) tumors contain a subpopulation of cells with stem cell features, termed brain cancer stem-like cells (bCSC), which are thought to be involved in tumorigenesis, treatment resistance and recurrence. The epidermal growth factor receptor (EGFR) and the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185454/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.113 |
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