Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells

Hyperactivation of Epidermal Growth Factor Receptor (EGFR) tyrosine kinase is prevalent in human lung cancer and its inhibition by the tyrosine kinase inhibitors (TKIs), including gefitinib and erlotinib, initially controls tumor growth. However, most patients ultimately relapse due to the developme...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wu, Kai, Chang, Qingshan, Lu, Yongju, Qiu, Ping, Chen, Bailing, Thakur, Chitra, Sun, Jiaying, Li, Lingzhi, Kowluru, Anjaneyulu, Chen, Fei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2013
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926838/
https://ncbi.nlm.nih.gov/pubmed/24280348
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