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Reactive oxygen species contribute to arsenic-induced EZH2 phosphorylation in human bronchial epithelial cells and lung cancer cells

Our previous studies suggested that arsenic is able to induce serine 21 phosphorylation of the EZH2 protein through activation of JNK, STAT3, and Akt signaling pathways in the bronchial epithelial cell line, BEAS-2B. In the present report, we further demonstrated that reactive oxygen species (ROS) w...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Li, Lingzhi, Qiu, Ping, Chen, Bailing, Lu, Yongju, Wu, Kai, Thakur, Chitra, Chang, Qingshan, Sun, Jiaying, Chen, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401465/
https://ncbi.nlm.nih.gov/pubmed/24582688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.02.005
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