Reactive oxygen species contribute to arsenic-induced EZH2 phosphorylation in human bronchial epithelial cells and lung cancer cells

Our previous studies suggested that arsenic is able to induce serine 21 phosphorylation of the EZH2 protein through activation of JNK, STAT3, and Akt signaling pathways in the bronchial epithelial cell line, BEAS-2B. In the present report, we further demonstrated that reactive oxygen species (ROS) w...

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Gepubliceerd in:Toxicol Appl Pharmacol
Hoofdauteurs: Li, Lingzhi, Qiu, Ping, Chen, Bailing, Lu, Yongju, Wu, Kai, Thakur, Chitra, Chang, Qingshan, Sun, Jiaying, Chen, Fei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401465/
https://ncbi.nlm.nih.gov/pubmed/24582688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.02.005
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