JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic

The molecular mechanisms by which arsenic (As(3+)) causes human cancers remain to be fully elucidated. Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of polycomb-repressive complexes 2 (PRC2) that promotes trimethylation of lysine 27 of histone H3, leading to altered expression of tumor...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Bailing, Liu, Jia, Chang, Qingshan, Beezhold, Kevin, Lu, Yongju, Chen, Fei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570498/
https://ncbi.nlm.nih.gov/pubmed/23255093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23030
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